Nodular clear cell hidradenoma: a rare case with similarities to metastatic clear renal cell carcinoma [version 1; referees: 1 approved]

Hidradenoma is presented as a benign small, firm and solitary nodule. Cytological study reveals a lesion mainly composed by two types of cells. The majority of the cases show a greater amount of a polyhedral and slightly basophilic cell type. Here we present a case with a predominance of a larger, rounded-shaped pale to clear cell type, which is characteristic of clear cell hidradenoma. Our case is of interest as, to the authors’ knowledge, no other related publication has described such striking similarities to metastatic clear renal cell carcinoma. Since the prognosis of these two conditions differs dramatically, a differential diagnosis based on immunohistochemistry is highlighted. José M Mir-Bonafé ( ) Corresponding author: [email protected] Mir-Bonafé JM, Santos-Briz Á, González M and Fernández-López E. How to cite this article: Nodular clear cell hidradenoma: a rare case 2013, :213 (doi: with similarities to metastatic clear renal cell carcinoma [version 1; referees: 1 approved] F1000Research 2 ) 10.12688/f1000research.2-213.v1 © 2013 Mir-Bonafé JM . This is an open access article distributed under the terms of the , Copyright: et al Creative Commons Attribution Licence which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Data associated with the article are available under the terms of the (CC0 1.0 Public domain dedication). Creative Commons Zero "No rights reserved" data waiver The author(s) declared that no grants were involved in supporting this work. Grant information: Competing interests: No competing interests were disclosed. 11 Oct 2013, :213 (doi: ) First published: 2 10.12688/f1000research.2-213.v1 1 2 1